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PhD candidate 'Electrophysiology of Retina'

3 years

Functieomschrijving

We have a vacant position for a PhD student - Electrophysiology of Retina. Join a PhD program in retinal development and immerse yourself in cutting-edge research to unlock the secrets of the human retina organoids from stem cells. With state-of-the-art techniques, you'll have the opportunity to make a real impact by developing innovative solutions for ocular diseases. Advance your career and change the future of eye care: This program offers you a unique opportunity to be at the forefront of scientific discovery. Apply now and take your passion and creativity to the next level!

The Department of Ophthalmology of the Radboud University Medical Center is a global leader in the field of multifactorial and genetic retinal eye diseases. The research of the department is focused on retinal forms of blindness that affect large numbers of patients worldwide, especially inherited retinal degenerations (IRDs), such as retinitis pigmentosa, and age-related macular degeneration (AMD). Our aim is to develop personalized treatment and prevention options using metabolomics, natural history studies and genetic profiles combined with imaging parameters, and artificial intelligence. Our ongoing research activities include genome-wide associations studies, development of eye-on-a-chip and patient-specific stem cell-derived retinal in vitro models, complement assays, and antisense oligonucleotide and CRISPR-cas9 technology.

Taks and responsibilities
  • Design and lead experiments to record electroretinographic signals with MEA and patch clamp or/and calcium imaging signals from retinal organoids and mouse retina.
  • Perform analysis of recorded data.
  • Collaborate with other team members to generate functional organoids for retinal research.
  • Interpret data and communicate results effectively to the team and stakeholders.
  • Publish findings in peer-reviewed journals.
We offer a friendly, stimulating, international and multidisciplinary environment. Nijmegen has beautiful nature, perfect for hiking, biking, and swimming.

Profiel

You are an ambitious PhD candidate with the ability to work both autonomously and interact efficiently within a multidisciplinary team.

Moreover you have: 
  • A master’s degree in (Medical) Biology, biomedical science, and relevant filed. 
  • Experimental knowledge in electrophysiology (patch clamp, multi-electrode array) , ideally in functional imaging, cell/tissue culture or molecular biology is an advantage.
  • A solid background in biology, ideally in neuroscience.
  • Background in statistics and data analysis.
  • Programming experience in Python, Matlab, R or similar is ideal.
  • Good organizational skills.

Organisatie

The department of Ophthalmology has approximately 120 employees, holds 8 ophthalmic subspecialties, each at an academic level. Our main focus of interest lies with the diagnosis and treatment of retinal diseases which accounts for over half of the patient care provided by the department. Our department is internationally renowned for its expertise on retinal disease.  Examples are inherited retinal diseases, age-related macular degeneration, diabetes mellites and vitreoretinal surgery.

Our scientific research lines match the clinical focus and is directed at retinal disorders. We have an enthusiastic team of researchers who collaborate collaborating in several research lines. Our team includes 2 senior PI’s, 2 junior levels PI’s, one research fellow, 7 PhD students and 2 research technicians.
The department has a large clinical trial center that currently houses over 35 trials. The department's research and clinical trials often target innovative treatment methods, such as gene therapy and RNA therapy.

Radboudumc
Welcome to Radboud university medical center (Radboudumc), where scientific breakthroughs are born through the curiosity and passion of our collaborating researchers in a vibrant environment. We believe trust and excitement are crucial elements to achieving our goals, and we approach our research as teams and with the utmost rigor to make a significant impact on health and healthcare. Our researchers are driven by their fascination with the biological, psychological, and sociological mechanisms underlying health and healthcare. They collaborate with partners from all over the world to improve health outcomes for all. Radboudumc unites patient care, research, education, and corporate learning, which allows us to approach our mission to shape the health and healthcare of the future in an innovative and person-centered way.

Our ambition is to lead the way in the pursuit of prevention, sustainability, meaningful care. We believe that through our research, we can significantly improve the health and well-being of society. Join us on our mission to make a difference in healthcare. Become a part of our community of gifted researchers, professionals or patient partners who are dedicated to making a real impact on population health and healthcare. 

Read what it is like to do a PhD at the Radboud University Medical Center.

Arbeidsvoorwaarden

At Radboud university medical center, you build on your future. We are committed to providing the best care, education, and research. And we are true to our word, because we help you develop and seize opportunities and give you the room to grow. As an employer, we believe that employees should feel vital and happy at work in all stages of life. We are also committed to creating a healthy and safe working environment. Our employment conditions contribute to that. What we offer:
  • The salary depends on education. Scale 10 will be offered to MSc medical graduates; a gross monthly salary between €3.493 and € 5.504. Those holding degrees in other disciplines will be offered scale 10A: upon commencement of employment, you will start at scale 10A, step 0 (€ 3.017 based on a full-time appointment). Over a maximum period of 4 years, you will progress to scale 10A, step 3 (€3.824 based on a full-time appointment). You will also receive an 8% holiday allowance, an 8.3% end-of-year bonus, and a 47% to 72% bonus for working unsocial hours.
  • Plenty of opportunities to develop yourself. For example, you can follow various courses via our online learning environment. A lot of attention will also be paid to your wellbeing and vitality. For instance, you can take advantage of:
    • 40% discount on gym membership at the Radboud Sports Center.
    • the Company Support Team and a personal coach if you experience a life-changing event.
    • a financially favorable option to work less through a generation scheme if you are approaching state retirement age.
    • support with achieving a good work-life balance at every stage of your life. This includes advice and training (from ‘Millennial Dilemmas’ to ‘Your Career After 57’), activities at our own mindfulness center, and informal caregiving consultations if you have any questions about combining your work and caregiving tasks at home.
  • 168 vacation hours per year based on a 36-hour working week. Want more vacation? You can buy additional vacation hours with your end-of-year bonus.
  • 26 weeks of parental leave, of which 9 weeks are paid.
  • Extra-favorable leave conditions. For example, our short-term caregiving leave is not 2 but 4 weeks per year and even 12 weeks per year for partner and child.
  • Pension accrual with the ABP Pension Fund. Radboud university medical center pays 70% of the pension contribution.
  • Discount on the supplementary packages of two collective health insurance policies and on ten other types of insurance, from home insurance to legal assistance.
  • travel allowance via our Employment Conditions Selection Model and a working-from-home allowance of €2 per day.

Opmerkingen en contactinformatie

Any questions? Or wondering what it is like to work at Radboudumc? Then email to Dr. Zohreh Hosseinzadeh, assistant professor. Use the Apply button to submit your application.